Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel
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چکیده
منابع مشابه
Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel.
Hydrotropic polymers (HPs) and their micelles have been recently developed as vehicles for delivery of poorly water-soluble drugs, such as paclitaxel (PTX), by oral administration. The release of PTX from HP micelles, however, was slow and it took more than a day for complete release of the loaded PTX. Since the gastrointestinal (GI) transit time is known to be only several hours, pH-sensitive ...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2008
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2008.07.004